SCHEMBL3123282

SCHEMBL3123282

FC1(F)CCC1(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4131162 0.73
SCHEMBL726127 0.71
SCHEMBL2775660 0.67
SCHEMBL63852 0.64
SCHEMBL6305646 0.64
SCHEMBL11800150 0.62
SCHEMBL11796069 0.62
SCHEMBL14188760 0.61
SCHEMBL11801107 0.58
SCHEMBL9908376 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2787076-B1 METHOD FOR EVALUATING DRUG SENSITIVITY AND DISEASE VULNERABILITY BY ANALYZING CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN GENE TOKYO METROPOLITAN INST MEDICAL SCIENCE (JP) 2019-08-28 EP claimed
US-20170357750-A1 METHOD FOR EVALUATING DRUG SENSITIVITY AND DISEASE VULNERABILITY BY ANALYZING CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN GENE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) 2017-12-14 US claimed
EP-2787076-A1 METHOD FOR EVALUATING DRUG SENSITIVITY AND SUSCEPTIBILITY TO DISEASES BY ANALYZING GENE FOR PROTEIN CAPABLE OF BINDING TO CYCLIC-AMP-RESPONSIVE SEQUENCE Tokyo Metropolitan Institute of Medical Science (JP) 2014-10-08 EP claimed
US-20140243237-A1 METHOD FOR EVALUATING DRUG SENSITIVITY AND DISEASE VULNERABILITY BY ANALYZING CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN GENE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) 2014-08-28 US claimed
EP-1895016-B1 Method of evaluating drug sensitivity by analyzing GIRK channel genes TOKYO METROPOLITAN ORG MED RES (JP) 2010-07-14 EP claimed
US-20090092972-A1 evaluating drug sensitivity or disease vulnerability, includes linking a gene polymorphism in a G-protein-activated inwardly rectifying K+ (GIRK) channel gene; determining if a human subject has an increased need for a narcotic analgesic to mitigate pain TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH 2009-04-09 US claimed
EP-1895016-A1 Method of evaluating drug sensitivity by analyzing GIRK channel genes Tokyo Metropolitan Organization for Medical Research (JP) 2008-03-05 EP claimed
US-4986928-A CLEANING COMPOUNDS, REFRIGERANTS, AEROSOL PROPELLANTS, BLOWING AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US claimed
EP-2787076-B1 METHOD FOR EVALUATING DRUG SENSITIVITY AND DISEASE VULNERABILITY BY ANALYZING CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN GENE TOKYO METROPOLITAN INST MEDICAL SCIENCE (JP) 2019-08-28 EP disclosed
US-10020406-B2 Protective film for solar cell and solar cell comprising the same LG CHEM, LTD. (KR) 2018-07-10 US disclosed
EP-2711179-B1 PROTECTION FILM FOR SOLAR CELL APPLICATION AND SOLAR CELL HAVING SAME LG CHEMICAL LTD (KR) 2018-07-04 EP disclosed
US-20170357750-A1 METHOD FOR EVALUATING DRUG SENSITIVITY AND DISEASE VULNERABILITY BY ANALYZING CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN GENE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE (JP) 2017-12-14 US disclosed
US-9727691-B2 Method for evaluating drug sensitivity and disease vulnerability by analyzing cyclic AMP responsive element binding protein gene TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE 2017-08-08 US disclosed
EP-2787076-A1 METHOD FOR EVALUATING DRUG SENSITIVITY AND SUSCEPTIBILITY TO DISEASES BY ANALYZING GENE FOR PROTEIN CAPABLE OF BINDING TO CYCLIC-AMP-RESPONSIVE SEQUENCE Tokyo Metropolitan Institute of Medical Science (JP) 2014-10-08 EP disclosed
US-4986928-A CLEANING COMPOUNDS, REFRIGERANTS, AEROSOL PROPELLANTS, BLOWING AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US disclosed
US-4625011-A Neutralization of alkali metal catalysts in organopolysiloxanes DOW CORNING CORPORATION (US) 1986-11-25 US disclosed
EP-0129318-A1 Neutralization of alkali metal catalysts in organopolysiloxanes DOW CORNING CORPORATION (US) 1984-12-27 EP disclosed
US-4267297-A CONTAINING ALKOXYLATED SILOXANES, ALKOXYSILANES AND AMINOALKOXYSILANES TORAY SILICONE COMPANY, LTD. (JP) 1981-05-12 US disclosed
US-3954893-A INHALATION ANESTHETICS W. R. GRACE & CO. (US) 1976-05-04 US disclosed
US-3870797-A Anesthetic halogenated cyclobutanes W. R. GRACE & CO.-CONN. 1975-03-11 US disclosed