SCHEMBL31233320

SCHEMBL31233320

COc1cc(O)cc(O)c1C(=O)C=Cc1ccc(O)c(CC=C(C)C)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.64
PTPN1 P18031 3/20 0.64
MAPT P10636 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
KCNA3 P22001 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
AKR1B10 O60218 1/20 0.60
AKR1B1 P15121 1/20 0.60
AKR1C3 P42330 1/20 0.60
PDPK1 O15530 1/20 0.60
TTR P02766 1/20 0.60
ALOX5 P09917 1/20 0.60
PTGS1 P23219 1/20 0.59
PTGS2 P35354 1/20 0.59
CYP3A4 P08684 3/20 0.58
KDM4E B2RXH2 2/20 0.58
HPGD P15428 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
MCL1 Q07820 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1659323 1.00 CYP19A1 (0.64) CYP19A1PTPN1MAPTMEN1KMT2A
SCHEMBL30384586 0.90 PTPN1 (0.74) CYP19A1PTPN1MAPTMEN1KMT2A
SCHEMBL4216620 0.90 PTPN1 (0.74) CYP19A1PTPN1MAPTMEN1KMT2A
SCHEMBL30383163 0.85 MEN1 (0.65) MAPTMEN1KMT2AKCNA3NPSR1
SCHEMBL3889916 0.85 MEN1 (0.65) MAPTMEN1KMT2AKCNA3NPSR1
SCHEMBL25206745 0.85 MEN1 (0.65) MAPTMEN1KMT2AKCNA3NPSR1
SCHEMBL1938672 0.82 MEN1 (0.83) MAPTMEN1KMT2AKCNA3NPSR1
SCHEMBL1938668 0.82 MEN1 (0.83) MAPTMEN1KMT2AKCNA3NPSR1
SCHEMBL25279943 0.80 MGAM (0.63) CYP19A1PTPN1MAPTMEN1KMT2A
SCHEMBL25234217 0.80 MGAM (0.63) CYP19A1PTPN1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed