Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24090418 | 1.00 | MEN1 (0.47) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL21184043 | 0.96 | MEN1 (0.46) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL21177695 | 0.87 | MEN1 (0.44) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL21177822 | 0.87 | EPHX2 (0.39) | MEN1KMT2ASTSEPHX2GPR183 | |
| SCHEMBL21184035 | 0.86 | MEN1 (0.43) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL21177633 | 0.86 | MEN1 (0.43) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL21183961 | 0.83 | MEN1 (0.41) | MEN1KMT2ASTSEPHX2MAPT | |
| SCHEMBL30354215 | 0.83 | PYGL (0.36) | KMT2A | |
| SCHEMBL21183978 | 0.82 | KMT2A (0.37) | MEN1KMT2AMAPTGPR183SMN1; SMN2 | |
| SCHEMBL21184096 | 0.81 | MEN1 (0.38) | MEN1KMT2AEPHX2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754861-A | Substituted alkynylene compounds as anticancer agents | 奥里吉恩肿瘤学有限公司 | 2024-10-11 | — | — | CN | disclosed |