Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.68 |
| ▸ | HTR1A | P08908 | 17/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20615067 | 0.94 | SLC6A2 (0.70) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL29003883 | 0.89 | SLC6A2 (0.71) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL3123426 | 0.82 | SLC6A2 (0.54) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL24180233 | 0.82 | SLC6A2 (0.70) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL3123273 | 0.80 | SLC6A2 (0.56) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL234010 | 0.80 | SLC6A2 (0.81) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL3466964 | 0.79 | SLC6A2 (0.79) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL19703137 | 0.79 | SLC6A2 (0.73) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL3129709 | 0.79 | SLC6A2 (0.55) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL22278138 | 0.78 | SLC6A2 (0.62) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |