Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20615067 | 0.84 | SLC6A2 (0.70) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL22296699 | 0.83 | SLC6A2 (0.44) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL2300405 | 0.81 | SLC6A4 (0.71) | SLC6A2HTR1ASLC6A3SLC6A4HTR2C | |
| SCHEMBL3123273 | 0.80 | SLC6A2 (0.56) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL3123418 | 0.79 | SLC6A2 (0.68) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL3121315 | 0.79 | SLC6A2 (0.41) | SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL5367403 | 0.78 | HTR2C (0.54) | SLC6A2HTR1ASLC6A3SLC6A4HTR2C | |
| SCHEMBL4699077 | 0.77 | PDE4A (0.41) | SLC6A2HTR1ASLC6A3SLC6A4TIPARP | |
| SCHEMBL941030 | 0.77 | SLC6A2 (0.58) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL83203 | 0.77 | SLC6A2 (0.62) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |