SCHEMBL31234428

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	18/20	0.57

▸	KEAP1	Q14145	1/20	0.54

▸	ECE1	P42892	1/20	0.54

▸	GLP1R	P43220	1/20	0.54

▸	MUS81	Q96NY9	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30094127	0.96	IL23R (0.57)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL30595758	0.94	IL23R (0.57)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL7149265	0.88	IL23R (0.60)	IL23RKEAP1
SCHEMBL30607340	0.88	GLP1R (0.59)	IL23RECE1GLP1RMUS81
SCHEMBL30571122	0.87	PTH1R (0.60)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL31182536	0.87	PTH1R (0.62)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL30607281	0.86	PTH1R (0.65)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL31013468	0.86	PTH1R (0.59)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL31013478	0.86	PTH1R (0.59)	IL23RKEAP1ECE1GLP1RMUS81
SCHEMBL30645551	0.85	PRMT1 (0.57)	IL23RECE1GLP1RMUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-118895244-A	Polypeptide for improving NK cell killing activity and application thereof	济南科汛智能科技有限公司	2024-11-05	—	—	CN	disclosed