Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 18/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157397 | 0.92 | IL23R (0.56) | IL23RKEAP1 | |
| SCHEMBL7151611 | 0.92 | IL23R (0.62) | IL23R | |
| SCHEMBL30595758 | 0.89 | IL23R (0.57) | IL23RKEAP1PTH1R | |
| SCHEMBL7155308 | 0.89 | IL23R (0.58) | IL23R | |
| SCHEMBL31234428 | 0.88 | IL23R (0.57) | IL23RKEAP1 | |
| SCHEMBL30185452 | 0.88 | UTS2R (0.54) | IL23RPTH1R | |
| SCHEMBL30094127 | 0.87 | IL23R (0.57) | IL23RKEAP1PTH1R | |
| SCHEMBL7157963 | 0.87 | IL23R (0.62) | IL23R | |
| SCHEMBL7153463 | 0.86 | KISS1R (0.57) | IL23R | |
| SCHEMBL7154197 | 0.85 | KISS1R (0.61) | IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144211-A1 | Peptide inhibitors of inflammation mediated by selectins | CENTOCOR, INC. | 2003-07-31 | — | — | US | disclosed |
| US-6528487-B1 | Including GMP-140, ELAM-1, and lymphocyte-homing receptor. | CENTOCOR, INC. | 2003-03-04 | — | — | US | disclosed |
| EP-0608260-A1 | PEPTIDE INHIBITORS OF INFLAMMATION MEDIATED BY SELECTINS | CENTOCOR, INC. (US) | 1994-08-03 | — | — | EP | disclosed |
| WO-1993005070-A1 | PEPTIDE INHIBITORS OF INFLAMMATION MEDIATED BY SELECTINS | CENTOCOR, INC. (US) | 1993-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144211-A1 | Peptide inhibitors of inflammation mediated by selectins | SELL, SELPLG, ELANE | IL23R 651/4885KEAP1 4180/4885PTH1R 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.