Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510027 | 0.85 | TDP1 (0.46) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL12598205 | 0.84 | HCRTR2 (0.44) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL15931187 | 0.84 | HCRTR2 (0.41) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL16520385 | 0.84 | HCRTR2 (0.41) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL15931189 | 0.83 | HCRTR2 (0.40) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL12598988 | 0.82 | TDP1 (0.44) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL7611276 | 0.82 | TDP1 (0.44) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL30096683 | 0.81 | TDP1 (0.42) | HCRTR2TDP1GAAMEN1KMT2A | |
| SCHEMBL21607436 | 0.81 | TDP1 (0.42) | HCRTR2TDP1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30096699 | 0.79 | TDP1 (0.41) | HCRTR2TDP1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024243025-A1 | NAPHTHYL-SUBSTITUTED PYRIDO[4,3-D]PYRIMIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2024-11-28 | — | — | WO | disclosed |