Sugi Predict

Sugi Predict / Compounds / SCHEMBL510027

SCHEMBL510027

SCHEMBL510027

CC(C)(C)OC(=O)NCC1(CO)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.46
▸ HCRTR2 O43614 1/20 0.43
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ GAA P10253 1/20 0.40
▸ CA12 O43570 2/20 0.39
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ EPHX1 P07099 1/20 0.39
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ DRD2 P14416 2/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ CACNA1H O95180 1/20 0.36
▸ APLNR P35414 1/20 0.36
▸ FPR3 P25089 1/20 0.35
▸ FPR2 P25090 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12598988 0.93 TDP1 (0.44) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL7611276 0.93 TDP1 (0.44) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL21607436 0.92 TDP1 (0.42) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL30158378 0.89 TDP1 (0.41) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL12598205 0.89 HCRTR2 (0.44) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL29778280 0.88 TDP1 (0.41) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL25576178 0.86 TDP1 (0.47) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL1979180 0.85 MEN1 (0.39) TDP1HCRTR2MEN1KMT2AGAA
SCHEMBL1978460 0.85 USP2 (0.42) TDP1HCRTR2MEN1KMT2AEPHX1
SCHEMBL30096683 0.85 TDP1 (0.42) TDP1HCRTR2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492210-B2 Tricyclic compounds and their use HUTCHISON MEDIPHARMA LIMITED (CN) 2025-12-09 — — US disclosed
US-20250353817-A1 INTERLUKIN-17A INHIBITORS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-11-20 — — US disclosed
EP-4491625-A1 BENZO BICYCLIC COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF Guangzhou Unirise Pharmaceutical Co., Ltd. (CN) 2025-01-15 — — EP disclosed
CN-118974037-A Benzobicyclo compound and preparation method and application thereof 广州市联瑞制药有限公司 2024-11-15 — — CN disclosed
EP-4069700-B1 MACROCYCLES FOR USE IN TREATING DISEASE TURNING POINT THERAPEUTICS INC (US) 2024-07-03 — — EP disclosed
CN-118239947-A Compound, intermediate, preparation method, pharmaceutical composition and application 上海艾力斯医药科技股份有限公司 2024-06-25 — — CN disclosed
US-20240083900-A1 PYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS BTK INHIBITORS BIOGEN MA INC. (US) 2024-03-14 — — US disclosed
CN-117486890-A Tricyclic compounds and uses thereof 和记黄埔医药（上海）有限公司 2024-02-02 — — CN disclosed
CN-117486888-A Tricyclic compounds and uses thereof 和记黄埔医药（上海）有限公司 2024-02-02 — — CN disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 — — US disclosed
WO-2010042851-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS ACHAOGEN, INC. (US) 2010-04-15 — — WO disclosed
WO-2010042850-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS ACHAOGEN, INC. (US) 2010-04-15 — — WO disclosed
WO-2009067692-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS ACHAOGEN, INC. (US) 2009-05-28 — — WO disclosed
US-7384952-B2 Pyrazolopyrimidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-06-10 — — US disclosed
EP-1857459-A2 Pyrazolopyrimidine compound and a process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 2007-11-21 — — EP disclosed
CN-100345853-C Pyrazolopyrimidine compound and method for producing the same TANABE SEIYAKU CO (JP) 2007-10-31 — — CN disclosed
US-20060135525-A1 Pyrazolopyrimidine compound and a process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2006-06-22 — — US disclosed
CN-1742013-A Pyrazolopyrimidine compound and method for producing the same TANABE SEIYAKU CO (JP) 2006-03-01 — — CN disclosed
EP-1585481-A2 PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 2005-10-19 — — EP disclosed
WO-2004064721-A2 A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 2004-08-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353817-A1 INTERLUKIN-17A INHIBITORS AND USES THEREOF IL17A, IL15, IL23R TDP1 3198/4885HCRTR2 4221/4885MEN1 2643/4885
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS TDP1 69/4885HCRTR2 546/4885MEN1 1514/4885
US-20240083900-A1 PYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS BTK INHIBITORS BTK, SYK, LYN TDP1 907/4885HCRTR2 4634/4885MEN1 3706/4885
US-12492210-B2 Tricyclic compounds and their use CYP2C8, CYP11B2, CYP3A7 TDP1 1280/4885HCRTR2 458/4885MEN1 2181/4885
US-20060135525-A1 Pyrazolopyrimidine compound and a process for preparing the same KCNJ2, KCNN2, KCNH2 TDP1 4645/4885HCRTR2 2084/4885MEN1 2842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.