SCHEMBL31236735

SCHEMBL31236735

Cc1cnc(-c2cc(C(=O)N[C@H](C)c3cnc(C(F)(F)F)nc3)cc(P(C)C)c2)s1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 20/20 0.70
P2RX2 Q9UBL9 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28698742 1.00 P2RX3 (0.70) P2RX3P2RX2
SCHEMBL28758889 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL30092072 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL30491097 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL17824236 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL21875573 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL28758893 0.88 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL28758886 0.86 P2RX3 (0.73) P2RX3P2RX2
SCHEMBL24071533 0.86 P2RX3 (0.69) P2RX3P2RX2
SCHEMBL29618652 0.86 P2RX3 (0.73) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072399-B Aromatic formamide compound and preparation method and medical application thereof 中国医药研究开发中心有限公司 2024-11-29 CN disclosed