SCHEMBL31236795

SCHEMBL31236795

O=C(CSc1ccccc1C(=O)O)Nc1ccccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.59
LMNA P02545 2/20 0.59
MEN1 O00255 2/20 0.59
GAA P10253 2/20 0.58
POLB P06746 1/20 0.58
APOBEC3A P31941 1/20 0.58
APOBEC3G Q9HC16 1/20 0.58
CYP1A2 P05177 1/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 1/20 0.56
KDM4E B2RXH2 1/20 0.54
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAPT P10636 1/20 0.51
CTSK P43235 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2111940 0.89 KMT2A (0.68) KMT2ALMNAMEN1GAAPOLB
SCHEMBL14066070 0.88 KMT2A (0.75) KMT2ALMNAMEN1GAACYP1A2
SCHEMBL4917378 0.82 KMT2A (0.66) KMT2ALMNAMEN1GAAPOLB
SCHEMBL1702460 0.82 KMT2A (0.55) KMT2AMEN1POLBALDH1A1HPGD
SCHEMBL17622776 0.81 TP53 (0.72) KMT2ALMNAMEN1GAAPOLB
SCHEMBL15694876 0.79 KMT2A (0.61) KMT2ALMNAMEN1GAAPOLB
SCHEMBL7460357 0.78 L3MBTL1 (0.49) KMT2ALMNAMEN1GAAPOLB
SCHEMBL8689526 0.78 KMT2A (0.68) KMT2ALMNAMEN1GAAPOLB
SCHEMBL7466702 0.77 PRMT5 (0.57) KMT2ALMNAMEN1GAAPOLB
SCHEMBL1702974 0.76 MAPT (0.52) KMT2ALMNAMEN1APOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12408914-B2 Systems and methods for customizing mechanical strength in stimuli-responsive bioabsorbable materials CILAG GMBH INTERNATIONAL (CH) 2025-09-09 US disclosed
EP-4543502-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS Cilag GmbH International (CH) 2025-04-30 EP disclosed
US-20240423617-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
US-20240423620-A1 COMPRESSIBLE SURGICAL ADJUNCTS, CARTRIDGES, AND CARTRIDGE ASSEMBLIES AND METHODS OF MAKING SURGICAL ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
WO-2024261659-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 WO disclosed