Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP18 | Q9UMW8 | 2/20 | 1.00 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14797847 | 0.80 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2CASP3 | |
| SCHEMBL14797848 | 0.80 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2CASP3 | |
| SCHEMBL9619486 | 0.80 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2CASP3 | |
| SCHEMBL9619484 | 0.80 | USP18 (0.67) | USP18UCHL5HSP90AA1USP2CASP3 | |
| SCHEMBL22822868 | 0.79 | HSP90AA1 (0.66) | USP18UCHL5HSP90AA1USP2CASP3 | |
| SCHEMBL11504417 | 0.76 | CYP1A2 (0.62) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL11820237 | 0.76 | HSP90AA1 (0.61) | USP18UCHL5HSP90AA1USP2MAOB | |
| SCHEMBL11820240 | 0.76 | HSP90AA1 (0.61) | USP18UCHL5HSP90AA1USP2MAOB | |
| SCHEMBL11504418 | 0.76 | CYP1A2 (0.62) | USP18UCHL5HSP90AA1USP2MAPT | |
| SCHEMBL11613815 | 0.75 | CYP1A2 (0.64) | USP18UCHL5HSP90AA1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |