Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CCR6 | P51684 | 2/20 | 0.61 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.61 |
| ▸ | APLNR | P35414 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17987877 | 1.00 | PAX8 (1.00) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL31307165 | 0.82 | PAX8 (0.69) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL19456445 | 0.82 | PAX8 (0.69) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL4916024 | 0.81 | PAX8 (0.68) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL12706320 | 0.81 | PAX8 (0.68) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL6715790 | 0.81 | PAX8 (0.67) | PAX8SMN1; SMN2KMT2ANPC1KDM4E | |
| SCHEMBL20101085 | 0.81 | PAX8 (0.67) | PAX8SMN1; SMN2KMT2ANPC1KDM4E | |
| SCHEMBL6715793 | 0.81 | PAX8 (0.67) | PAX8SMN1; SMN2KMT2ANPC1KDM4E | |
| SCHEMBL20101097 | 0.80 | CCR6 (0.68) | PAX8SMN1; SMN2CCR6CXCR5APLNR | |
| SCHEMBL20101022 | 0.79 | PAX8 (0.65) | PAX8SMN1; SMN2KMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |