Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.72 |
| ▸ | RELA | Q04206 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238310 | 0.89 | MAPT (0.91) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL24046921 | 0.88 | MAOB (0.77) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238508 | 0.86 | MAPT (0.66) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238446 | 0.85 | ABCB1 (0.85) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.85 | MAPT (1.00) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.85 | MAPT (1.00) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238403 | 0.84 | MAPT (0.92) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238437 | 0.84 | MAPT (0.78) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238456 | 0.83 | MAPT (0.76) | MAPTKDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL31238490 | 0.82 | MAPT (0.74) | MAPTKDM4EALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189504-A1 | BROAD - SPECTRUM ANTI VIRAL COMPOUNDS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2024-09-19 | — | — | WO | claimed |
| WO-2024189504-A1 | BROAD - SPECTRUM ANTI VIRAL COMPOUNDS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2024-09-19 | — | — | WO | disclosed |