Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | TNKS | O95271 | 4/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.64 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238531 | 0.88 | MAPT (0.72) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| 4,7-Dimethoxyflavone SCHEMBL3470601 | 0.87 | MAOB (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL30674795 | 0.82 | MAOB (0.83) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL30674786 | 0.82 | MAOB (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL30266579 | 0.82 | CYP3A4 (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL312254 | 0.82 | CYP3A4 (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL9142214 | 0.82 | MAOB (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL7656355 | 0.82 | MAOB (0.83) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| 7-Methoxyflavone SCHEMBL1373009 | 0.82 | TNKS (1.00) | MAOBCYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL24046925 | 0.82 | MAOB (0.64) | MAOBCYP3A4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |