Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238698 | 0.75 | TNF (0.49) | KMT2AGAAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL31238832 | 0.74 | TNF (0.45) | KMT2AGAAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL24512064 | 0.69 | KMT2A (0.42) | KMT2A | |
| SCHEMBL31696588 | 0.69 | HPGD (0.39) | KMT2ATSHRGAAMEN1SMN1; SMN2 | |
| SCHEMBL8270927 | 0.67 | KDM4E (0.59) | KMT2ATSHRGAAMEN1SMN1; SMN2 | |
| SCHEMBL21217924 | 0.66 | KMT2A (0.36) | KMT2A | |
| SCHEMBL31176818 | 0.66 | HPGD (0.41) | KMT2ATSHRGAAMEN1CASP3 | |
| SCHEMBL15988007 | 0.66 | KMT2A (0.48) | KMT2AGAASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL22121370 | 0.64 | KDM4E (0.44) | KMT2ATSHRGAAMEN1KAT2B | |
| SCHEMBL24928462 | 0.64 | TSHR (0.39) | KMT2ATSHRGAAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727925-A2 | PROCESS FOR THE PREPARATION OF A CHIRAL PYRROLO TRIAZOLE ALCOHOL | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024260932-A2 | PROCESS FOR THE PREPARATION OF A CHIRAL PYRROLO TRIAZOLE ALCOHOL | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-26 | — | — | WO | disclosed |