Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31696588 | 0.84 | HPGD (0.39) | TSHRHPGDHSD17B10GAAMEN1 | |
| SCHEMBL12532887 | 0.83 | MAPK1 (0.36) | HPGDHSD17B10GAAMEN1KMT2A | |
| SCHEMBL23115927 | 0.81 | AURKA (0.39) | TSHRHPGDHSD17B10GAAMEN1 | |
| SCHEMBL7417402 | 0.81 | KDM4E (0.38) | HPGDHSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL171958 | 0.76 | SMPD1 (0.41) | TSHRGAATP53MAPT | |
| SCHEMBL20661071 | 0.76 | CYP11B1 (0.36) | HPGDHSD17B10GAAMEN1KMT2A | |
| SCHEMBL31696418 | 0.75 | KAT2B (0.40) | TSHRHPGDHSD17B10GAAKAT2B | |
| SCHEMBL69696 | 0.75 | MEN1 (0.44) | HPGDMEN1KMT2ARAB9AMAPT | |
| SCHEMBL12532886 | 0.75 | MAPKAPK2 (0.40) | HPGDHSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL24213262 | 0.74 | DRD2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |