Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.44 |
| ▸ | CLK2 | P49760 | 12/20 | 0.44 |
| ▸ | CLK3 | P49761 | 10/20 | 0.44 |
| ▸ | WNT1 | P04628 | 6/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240391 | 0.90 | DYRK1A (0.42) | DYRK1ACLK2CLK3WNT1TBK1 | |
| SCHEMBL31240291 | 0.87 | DYRK1A (0.43) | DYRK1ACLK2CLK3WNT1JAK2 | |
| SCHEMBL26685743 | 0.83 | JAK2 (0.46) | DYRK1ACLK2CLK3WNT1JAK2 | |
| SCHEMBL26686193 | 0.83 | JAK2 (0.46) | DYRK1ACLK2CLK3WNT1JAK2 | |
| SCHEMBL31240369 | 0.82 | CHUK (0.47) | DYRK1ACLK2CLK3WNT1JAK2 | |
| SCHEMBL31240548 | 0.82 | TBK1 (0.46) | DYRK1AWNT1JAK2TBK1 | |
| SCHEMBL31240498 | 0.80 | CLK2 (0.52) | DYRK1ACLK2CLK3WNT1JAK2 | |
| SCHEMBL31240596 | 0.80 | CLK2 (0.48) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL31240749 | 0.80 | DYRK1A (0.44) | DYRK1ACLK2CLK3JAK2TBK1 | |
| SCHEMBL31240700 | 0.80 | CLK2 (0.58) | DYRK1ACLK2CLK3JAK2TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |