Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 9/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.43 |
| ▸ | CLK3 | P49761 | 7/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 6/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240451 | 0.91 | FYN (0.50) | CLK2DYRK1ACLK3WNT1FYN | |
| SCHEMBL31240498 | 0.87 | CLK2 (0.52) | CLK2DYRK1ACLK3CCNT1CDK9 | |
| SCHEMBL31240471 | 0.86 | PRMT5 (0.48) | CLK2DYRK1ACLK3CDK9WNT1 | |
| SCHEMBL31240708 | 0.82 | TBK1 (0.46) | — | |
| SCHEMBL31240580 | 0.82 | CLK2 (0.50) | CLK2DYRK1ACLK3WNT1MAPK14 | |
| SCHEMBL31240700 | 0.80 | CLK2 (0.58) | CLK2DYRK1ACLK3 | |
| SCHEMBL31240412 | 0.80 | CLK2 (0.51) | CLK2DYRK1ACLK3WNT1MAPK14 | |
| SCHEMBL31240417 | 0.79 | CCNB2 (0.53) | CLK2DYRK1ACLK3FYNMAPK14 | |
| SCHEMBL31240490 | 0.79 | CLK2 (0.47) | CLK2DYRK1ACLK3WNT1MAPK14 | |
| SCHEMBL31240312 | 0.79 | CLK2 (0.53) | CLK2DYRK1ACLK3FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |