Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.44 |
| ▸ | CLK2 | P49760 | 10/20 | 0.44 |
| ▸ | CLK3 | P49761 | 9/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240369 | 0.91 | CHUK (0.47) | DYRK1ACLK2CLK3CHUKINSR | |
| SCHEMBL31240583 | 0.84 | CLK2 (0.42) | DYRK1ACLK2CLK3CHUKINSR | |
| SCHEMBL26685953 | 0.83 | TLR8 (0.41) | DYRK1ACLK2CLK3CHUKAURKB | |
| SCHEMBL31240632 | 0.83 | CLK2 (0.41) | DYRK1ACLK2CLK3CHUKINSR | |
| SCHEMBL31240498 | 0.80 | CLK2 (0.52) | DYRK1ACLK2CLK3WNT1CCNT1 | |
| SCHEMBL31240596 | 0.80 | CLK2 (0.48) | DYRK1ACLK2CLK3CHUKINSR | |
| SCHEMBL31240700 | 0.80 | CLK2 (0.58) | DYRK1ACLK2CLK3 | |
| SCHEMBL31240412 | 0.79 | CLK2 (0.51) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL31240258 | 0.79 | DYRK1A (0.44) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL31240586 | 0.77 | CLK2 (0.52) | DYRK1ACLK2CLK3WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |