Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 10/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.50 |
| ▸ | CLK3 | P49761 | 8/20 | 0.50 |
| ▸ | JAK2 | O60674 | 5/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 3/20 | 0.46 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240458 | 0.86 | CHUK (0.51) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240486 | 0.84 | CLK2 (0.55) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240405 | 0.84 | CLK2 (0.59) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240700 | 0.83 | CLK2 (0.58) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240683 | 0.81 | DYRK1A (0.54) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240376 | 0.81 | CLK2 (0.62) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240421 | 0.81 | MAPK8 (0.47) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240343 | 0.79 | CLK2 (0.63) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240587 | 0.79 | CLK2 (0.56) | CLK2DYRK1ACLK3JAK2TYK2 | |
| SCHEMBL31240306 | 0.79 | DYRK1A (0.71) | CLK2DYRK1ACLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |