Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 11/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.56 |
| ▸ | CLK3 | P49761 | 9/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 4/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | WNT1 | P04628 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240700 | 0.92 | CLK2 (0.58) | CLK2DYRK1ACLK3JAK2JAK1 | |
| SCHEMBL31240405 | 0.90 | CLK2 (0.59) | CLK2DYRK1ACLK3EGFRJAK2 | |
| SCHEMBL31240705 | 0.89 | CLK2 (0.57) | CLK2DYRK1ACLK3EGFRJAK2 | |
| SCHEMBL31240306 | 0.87 | DYRK1A (0.71) | CLK2DYRK1ACLK3WNT1 | |
| SCHEMBL31240326 | 0.86 | TBK1 (0.58) | CLK2DYRK1ACLK3CCNT1CDK9 | |
| SCHEMBL31240417 | 0.86 | CCNB2 (0.53) | CLK2DYRK1ACLK3 | |
| SCHEMBL31240492 | 0.86 | DYRK1A (0.52) | CLK2DYRK1ACLK3EGFRPDPK1 | |
| SCHEMBL31240495 | 0.86 | CLK2 (0.53) | CLK2DYRK1ACLK3EGFRCCNT1 | |
| SCHEMBL31240550 | 0.86 | DYRK1A (0.51) | CLK2DYRK1ACLK3EGFRPDPK1 | |
| SCHEMBL31240343 | 0.85 | CLK2 (0.63) | CLK2DYRK1ACLK3PDPK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |