Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | MARK3 | P27448 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240461 | 0.88 | JAK2 (0.52) | JAK2LRRK2PDPK1KDRMAPKAPK2 | |
| SCHEMBL31240348 | 0.87 | JAK2 (0.53) | JAK2LRRK2PDPK1KDRMAPKAPK2 | |
| SCHEMBL31240265 | 0.87 | JAK2 (0.61) | JAK2LRRK2PDPK1KDRMAPKAPK2 | |
| SCHEMBL31240361 | 0.86 | JAK2 (0.47) | JAK2LRRK2PDPK1KDRMAPKAPK2 | |
| SCHEMBL31240611 | 0.85 | ROCK1 (0.53) | JAK2LRRK2PKMYT1SYKROCK1 | |
| SCHEMBL31240612 | 0.85 | ROCK1 (0.53) | JAK2LRRK2PKMYT1SYKROCK1 | |
| SCHEMBL31240431 | 0.85 | NPC1 (0.48) | JAK2LRRK2KDRPLK4DAPK3 | |
| SCHEMBL31240740 | 0.84 | JAK2 (0.47) | JAK2LRRK2PDPK1KDRMAPKAPK2 | |
| SCHEMBL31240466 | 0.83 | JAK2 (0.54) | JAK2LRRK2PDPK1KDRPLK4 | |
| SCHEMBL31240314 | 0.82 | JAK2 (0.68) | JAK2LRRK2PDPK1KDRMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |