Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | ULK1 | O75385 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 3/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240612 | 1.00 | ROCK1 (0.53) | ROCK1PKMYT1LYNTXKSYK | |
| SCHEMBL31240431 | 0.92 | NPC1 (0.48) | ROCK1JAK2MAP2K4LRRK2ULK1 | |
| SCHEMBL26685726 | 0.91 | JAK2 (0.48) | ROCK1PKMYT1LYNTXKSYK | |
| SCHEMBL31420120 | 0.91 | JAK2 (0.48) | ROCK1PKMYT1LYNTXKSYK | |
| SCHEMBL31240407 | 0.86 | JAK2 (0.63) | JAK2LRRK2ULK1JAK1MAPK8 | |
| SCHEMBL31240571 | 0.86 | ROCK2 (0.45) | ROCK1JAK2LRRK2ULK1JAK1 | |
| SCHEMBL31240287 | 0.86 | TP53 (0.52) | ROCK1SYKBRAFJAK2 | |
| SCHEMBL31240424 | 0.85 | JAK2 (0.50) | ROCK1PKMYT1SYKRAF1BRAF | |
| SCHEMBL31240461 | 0.85 | JAK2 (0.52) | ROCK1JAK2LRRK2ULK1JAK1 | |
| SCHEMBL31240518 | 0.84 | PIK3C3 (0.48) | ROCK1JAK2LRRK2ULK1JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |