Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.54 |
| ▸ | WNT1 | P04628 | 6/20 | 0.54 |
| ▸ | CHUK | O15111 | 2/20 | 0.52 |
| ▸ | INSR | P06213 | 2/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686261 | 0.87 | DYRK1A (0.56) | DYRK1AWNT1PARP1CLK2CLK3 | |
| SCHEMBL30633374 | 0.87 | DYRK1A (0.56) | DYRK1AWNT1PARP1CLK2CLK3 | |
| SCHEMBL31240434 | 0.86 | CHUK (0.57) | DYRK1ACHUKINSRMAPK8CAMKK2 | |
| SCHEMBL31240564 | 0.84 | DYRK1A (0.48) | DYRK1AWNT1CHUKINSRMAPK8 | |
| SCHEMBL31240495 | 0.82 | CLK2 (0.53) | DYRK1AWNT1CHUKINSRMAPK8 | |
| SCHEMBL31240437 | 0.82 | MAPK8 (0.55) | DYRK1ACHUKINSRMAPK8CAMKK2 | |
| SCHEMBL31240414 | 0.81 | CCNT1 (0.49) | DYRK1ACHUKINSRMAPK8CAMKK2 | |
| SCHEMBL31240700 | 0.77 | CLK2 (0.58) | DYRK1ACLK2CLK3TBK1 | |
| SCHEMBL26685962 | 0.76 | DYRK1A (0.43) | DYRK1AWNT1MAPK8MAP4K4CLK2 | |
| SCHEMBL31240705 | 0.76 | CLK2 (0.57) | DYRK1AWNT1CHUKINSRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |