Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 5/20 | 0.57 |
| ▸ | INSR | P06213 | 5/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.57 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.57 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 4/20 | 0.46 |
| ▸ | CLK3 | P49761 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240633 | 0.86 | CCNK (0.54) | MAP3K5CLK2CLK3DYRK1ACCNK | |
| SCHEMBL26686484 | 0.86 | CCNK (0.54) | MAP3K5CLK2CLK3DYRK1ACCNK | |
| SCHEMBL31240454 | 0.86 | DYRK1A (0.54) | CHUKINSRMAPK8CAMKK2CLK2 | |
| SCHEMBL31240495 | 0.84 | CLK2 (0.53) | CHUKINSRMAPK8CAMKK2CLK2 | |
| SCHEMBL31240437 | 0.84 | MAPK8 (0.55) | CHUKINSRMAPK8CAMKK2CLK2 | |
| SCHEMBL31240483 | 0.83 | MAP4K4 (0.53) | CHUKINSRMAPK8CAMKK2CLK2 | |
| SCHEMBL31240417 | 0.80 | CCNB2 (0.53) | ROCK2ROCK1CLK2CLK3DYRK1A | |
| SCHEMBL31240700 | 0.79 | CLK2 (0.58) | CLK2CLK3DYRK1ATBK1 | |
| SCHEMBL31240792 | 0.79 | CHUK (0.53) | CHUKINSRMAPK8CAMKK2MAP3K5 | |
| SCHEMBL31240705 | 0.78 | CLK2 (0.57) | CHUKINSRMAPK8CAMKK2CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |