Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.60 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926052 | 0.86 | RIOK2 (0.63) | RIOK2ANO1GSK3AMAPK10MAPK8 | |
| SCHEMBL1553776 | 0.81 | RIOK2 (0.74) | RIOK2GSK3AMAPK10MAPK8NPC1 | |
| SCHEMBL16879381 | 0.80 | MEN1 (0.64) | KCNJ5KCNJ3NPC1RAB9AALDH1A1 | |
| SCHEMBL30368230 | 0.79 | JAK2 (0.62) | KCNJ5KCNJ3ANO1KCNJ6 | |
| SCHEMBL31240687 | 0.78 | RIOK2 (0.67) | RIOK2GSK3AMAPK10NPC1RAB9A | |
| SCHEMBL31240655 | 0.78 | RIOK2 (0.66) | RIOK2ANO1NTRK1GSK3AMAPK10 | |
| SCHEMBL16620799 | 0.77 | RIOK2 (0.57) | RIOK2NTRK1GSK3AMAPK10NPC1 | |
| SCHEMBL30226568 | 0.77 | RIOK2 (0.57) | RIOK2NTRK1GSK3AMAPK10NPC1 | |
| SCHEMBL31729852 | 0.77 | KCNJ5 (0.74) | KCNJ5KCNJ3ANO1KCNJ6ALDH1A1 | |
| SCHEMBL31240723 | 0.75 | RIOK2 (0.66) | RIOK2GSK3AMAPK10MAPK8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |