Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | WNT3A | P56704 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.52 |
| ▸ | GSK3A | P49840 | 3/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.52 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240723 | 0.88 | RIOK2 (0.66) | RIOK2KMT2AMEN1RAB9AWNT3A | |
| SCHEMBL30367058 | 0.86 | RAB9A (0.61) | RIOK2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL25235255 | 0.86 | RIOK2 (0.67) | RIOK2KMT2AMEN1RAB9AWNT3A | |
| SCHEMBL31240687 | 0.86 | RIOK2 (0.67) | RIOK2KMT2AMEN1RAB9AWNT3A | |
| SCHEMBL31240823 | 0.85 | RIOK2 (0.66) | RIOK2KMT2AMEN1RAB9AMAPK10 | |
| SCHEMBL31240655 | 0.85 | RIOK2 (0.66) | RIOK2KMT2AMEN1MAPK10GSK3A | |
| SCHEMBL31240637 | 0.85 | RIOK2 (0.66) | RIOK2KMT2AMEN1RAB9AWNT3A | |
| SCHEMBL27926052 | 0.83 | RIOK2 (0.63) | RIOK2KMT2AMEN1RAB9AMAPK10 | |
| SCHEMBL29083803 | 0.82 | MAPK10 (0.75) | RIOK2KMT2AMEN1RAB9AWNT3A | |
| SCHEMBL15276220 | 0.82 | KMT2A (0.60) | RIOK2KMT2AMEN1RAB9AWNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| CN-102834387-A | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | BAYER CROPSCIENCE AG | 2012-12-19 | — | — | CN | disclosed |
| EP-2486031-A2 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2012-08-15 | — | — | EP | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| WO-2011042389-A2 | PHENYLPYRI(MI)DINYLAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | WO | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | RIOK2 2706/4885KMT2A 1070/4885MEN1 1254/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | RIOK2 2706/4885KMT2A 1070/4885MEN1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.