Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.66 |
| ▸ | GSK3A | P49840 | 2/20 | 0.66 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.59 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.56 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240668 | 0.85 | RIOK2 (0.67) | MAPK10GSK3ARIOK2L3MBTL1MAPK8 | |
| SCHEMBL31240659 | 0.85 | RIOK2 (0.74) | MAPK10GSK3ARIOK2MAPK8HIPK1 | |
| SCHEMBL31240658 | 0.84 | RIOK2 (0.65) | MAPK10GSK3ARIOK2L3MBTL1RAB9A | |
| SCHEMBL14156888 | 0.83 | KDM4E (0.57) | MAPK10GSK3ARIOK2L3MBTL1MAPK8 | |
| SCHEMBL31240609 | 0.83 | RIOK2 (0.61) | MAPK10GSK3ARIOK2MAPK8HIPK1 | |
| SCHEMBL18292480 | 0.83 | NR3C2 (0.54) | MAPK10GSK3ARIOK2L3MBTL1MAPK8 | |
| SCHEMBL31240786 | 0.81 | RIOK2 (0.62) | MAPK10GSK3ARIOK2MAPK8KMT2A | |
| SCHEMBL31240655 | 0.80 | RIOK2 (0.66) | MAPK10GSK3ARIOK2MAPK8HIPK1 | |
| SCHEMBL18194752 | 0.78 | L3MBTL1 (0.60) | MAPK10GSK3ARIOK2L3MBTL1MAPK8 | |
| SCHEMBL31240626 | 0.78 | GSK3A (0.60) | MAPK10GSK3ARIOK2MAPK8HIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |