SCHEMBL31240804

SCHEMBL31240804

N#Cc1cnccc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
AR P10275 11/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TRPA1 O75762 1/20 0.39
PRKCQ Q04759 4/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
PRKCD Q05655 3/20 0.38
PDE10A Q9Y233 1/20 0.38
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL507128 1.00 HTT (0.42) HTTARMEN1KMT2ATRPA1
Hydrochloric Acid SCHEMBL4572873 0.98 HTT (0.41) HTTARMEN1KMT2ATRPA1
SCHEMBL30947612 0.85 HTT (0.40) HTTARMEN1KMT2ANCOA3
SCHEMBL34463384 0.84 KMT2A (0.44) HTTARMEN1KMT2ANCOA3
SCHEMBL6122108 0.84 KMT2A (0.44) HTTARMEN1KMT2ANCOA3
SCHEMBL5244520 0.83 MEN1 (0.34) HTTARMEN1KMT2ATRPA1
SCHEMBL27896462 0.82 HDAC8 (0.38) MEN1KMT2A
SCHEMBL6672265 0.80 HTT (0.42) HTTMEN1KMT2ANCOA3
SCHEMBL1040750 0.80 SLC22A12 (0.38) PDE10A
SCHEMBL27896461 0.74 SLC22A12 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121591651-A 4-Trifluoromethyl-3-cyanopyridine compound and application thereof 贵州省天然产物研究中心 2026-03-03 CN disclosed
CN-115611806-B Preparation method of 4-trifluoromethyl-3-cyanopyridine 江苏中旗科技股份有限公司 2024-11-19 CN disclosed