Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240804 | 1.00 | HTT (0.42) | HTTARMEN1KMT2ATRPA1 | |
| Hydrochloric Acid SCHEMBL4572873 | 0.98 | HTT (0.41) | HTTARMEN1KMT2ATRPA1 | |
| SCHEMBL30947612 | 0.85 | HTT (0.40) | HTTARMEN1KMT2ANCOA3 | |
| SCHEMBL34463384 | 0.84 | KMT2A (0.44) | HTTARMEN1KMT2ANCOA3 | |
| SCHEMBL6122108 | 0.84 | KMT2A (0.44) | HTTARMEN1KMT2ANCOA3 | |
| SCHEMBL5244520 | 0.83 | MEN1 (0.34) | HTTARMEN1KMT2ATRPA1 | |
| SCHEMBL27896462 | 0.82 | HDAC8 (0.38) | MEN1KMT2A | |
| SCHEMBL6672265 | 0.80 | HTT (0.42) | HTTMEN1KMT2ANCOA3 | |
| SCHEMBL1040750 | 0.80 | SLC22A12 (0.38) | PDE10A | |
| SCHEMBL27896461 | 0.74 | SLC22A12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| CN-115611806-B | Preparation method of 4-trifluoromethyl-3-cyanopyridine | 江苏中旗科技股份有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118852123-A | Novel heterocyclic compounds as Pol theta inhibitors for the treatment and prevention of cancer and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2024-10-29 | — | — | CN | claimed |
| CN-118388402-A | Continuous preparation method of 3-cyano-4-trifluoromethyl pyridine | 山东京博生物科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118348182-A | Ultrahigh performance liquid chromatography central control analysis method for 3-cyano-4-trifluoromethylpyridine | 山东京博生物科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-114315709-B | Synthesis method of 4-trifluoromethyl nicotinic acid | 西安近代化学研究所 | 2024-05-10 | — | — | CN | claimed |
| CN-117199519-A | Electrolyte, preparation method and application thereof, and lithium battery | 北京纳米能源与系统研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-117085700-A | Preparation method and application method of special catalyst for dechlorination | 西安凯立新材料股份有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-115611806-A | Preparation method of 4-trifluoromethyl-3-cyanopyridine | 江苏中旗科技股份有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-114315709-A | Synthetic method of 4-trifluoromethyl nicotinic acid | 西安近代化学研究所 | 2022-04-12 | — | — | CN | claimed |
| CN-112110855-B | Method for preparing 3-cyano-4-trifluoromethylpyridine by using Ni-Fe/C bimetallic supported catalyst | 山东京博生物科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-108191749-B | Preparation method of flonicamid and intermediate 4-trifluoromethyl nicotinic acid thereof | 上海赫腾精细化工有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-112110855-A | Method for preparing 3-cyano-4-trifluoromethylpyridine by using Ni-Fe/C bimetallic supported catalyst | 山东京博生物科技有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-111153825-A | Method for preparing amide compound by using supported metal oxide catalytic material | 浙江大学 | 2020-05-15 | — | — | CN | claimed |
| CN-103694168-B | The preparation method of the chloro-4-trifluoromethyl-nicotinonitrile of a kind of 6- | GUIZHOU WYLTON JINGLIN ELECTRONIC MATERIAL CORP. (CN) | 2015-08-19 | — | — | CN | claimed |
| EP-2205083-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Merck Sharp & Dohme Corp. (US) | 2010-07-14 | — | — | EP | claimed |
| WO-2009045382-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | claimed |
| CN-101128470-A | Novel compounds | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | claimed |