Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31241039 | 0.84 | RAB9A (0.65) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL15305700 | 0.77 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL30008310 | 0.77 | SMN1; SMN2 (0.76) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL30008066 | 0.77 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL30008144 | 0.77 | RAB9A (1.00) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL31241128 | 0.76 | RAB9A (0.60) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL21555674 | 0.75 | RAB9A (0.42) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL15968991 | 0.74 | RAB9A (0.61) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL31241071 | 0.72 | RAB9A (0.97) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 | |
| SCHEMBL1849856 | 0.72 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2L3MBTL1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812505-A | PI5P4K gamma inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 贵州医科大学 | 2024-10-22 | — | — | CN | disclosed |