Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120860 | 0.92 | HTR2C (0.40) | HTR2CHTR2AKCNH2SSTR4HTR2B | |
| Trifluoroacetic Acid SCHEMBL3121822 | 0.85 | CHRNA3 (0.41) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| Trifluoroacetic Acid SCHEMBL6198900 | 0.84 | HTR2C (0.39) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| Trifluoroacetic Acid SCHEMBL3114765 | 0.84 | CHRNA3 (0.46) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| Trifluoroacetic Acid SCHEMBL3116407 | 0.84 | IRAK4 (0.38) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| Trifluoroacetic Acid SCHEMBL5585749 | 0.79 | HTR2C (0.35) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| Succinic Acid SCHEMBL15022004 | 0.79 | HTR2C (0.39) | HTR2CHTR2AKCNH2SSTR4SSTR1 | |
| SCHEMBL2639295 | 0.78 | HTR2C (0.42) | HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL4313537 | 0.78 | HTR2C (0.42) | HTR2CHTR2AKCNH2HTR2B | |
| SCHEMBL237951 | 0.78 | HTR2C (0.42) | HTR2CHTR2AKCNH2SSTR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513831-B1 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB PUBL (SE) | 2010-01-06 | — | — | EP | claimed |