Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 14/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31526935 | 0.94 | KRAS (0.45) | KRASMAPK3MAPK1 | |
| SCHEMBL31243078 | 0.89 | KRAS (0.52) | KRASMAPK3MAPK1 | |
| SCHEMBL31526978 | 0.86 | KRAS (0.47) | KRASMAPK3MAPK1 | |
| SCHEMBL31527436 | 0.86 | KRAS (0.41) | KRASMAPK3MAPK1 | |
| SCHEMBL31243091 | 0.85 | ATR (0.34) | — | |
| SCHEMBL30873335 | 0.85 | KRAS (0.47) | KRASMAPK3MAPK1 | |
| SCHEMBL29321588 | 0.85 | KRAS (0.47) | KRASMAPK3MAPK1 | |
| SCHEMBL29323624 | 0.85 | KRAS (0.47) | KRASMAPK3MAPK1 | |
| SCHEMBL31527104 | 0.85 | KRAS (0.47) | KRASMAPK3MAPK1 | |
| SCHEMBL31243114 | 0.84 | ATR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713330-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235286-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |