Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 11/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31243114 | 0.92 | ATR (0.33) | ATRRET | |
| SCHEMBL31243021 | 0.91 | ATR (0.32) | ATRRET | |
| SCHEMBL31527059 | 0.85 | ATR (0.33) | ATRRET | |
| SCHEMBL31243045 | 0.85 | KRAS (0.46) | — | |
| SCHEMBL31243053 | 0.83 | KRAS (0.32) | — | |
| SCHEMBL31526935 | 0.80 | KRAS (0.45) | — | |
| SCHEMBL31243078 | 0.73 | KRAS (0.52) | — | |
| SCHEMBL29323624 | 0.68 | KRAS (0.47) | — | |
| SCHEMBL30873335 | 0.68 | KRAS (0.47) | — | |
| SCHEMBL29321588 | 0.68 | KRAS (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713330-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235286-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |