Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937112 | 0.89 | CYP4F2 (0.34) | GAACYP4F2CYP4A11RETATR | |
| SCHEMBL30699417 | 0.86 | RET (0.33) | CYP4F2CYP4A11RETATR | |
| SCHEMBL30998808 | 0.85 | GAA (0.40) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL24802948 | 0.83 | GAA (0.39) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL20974775 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11RETALDH1A1ATR | |
| SCHEMBL29478900 | 0.79 | GAA (0.41) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL24373243 | 0.79 | GAA (0.41) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL26404734 | 0.78 | GAA (0.39) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL29937275 | 0.78 | GAA (0.39) | GAACYP4F2CYP4A11RETKDM4E | |
| SCHEMBL30161900 | 0.78 | CYP4F2 (0.41) | GAACYP4F2CYP4A11RETKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713330-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235286-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |