Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 4/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31243076 | 0.89 | GAA (0.37) | CYP4F2CYP4A11RETATRGAA | |
| SCHEMBL30699417 | 0.85 | RET (0.33) | CYP4F2CYP4A11RETATR | |
| SCHEMBL24802947 | 0.84 | CYP4F2 (0.36) | CYP4F2CYP4A11RETATRGAA | |
| SCHEMBL28484352 | 0.80 | CYP4F2 (0.38) | CYP4F2CYP4A11RETATRGAA | |
| SCHEMBL30300121 | 0.80 | CYP4F2 (0.38) | CYP4F2CYP4A11RETATRGAA | |
| SCHEMBL29936966 | 0.79 | RET (0.35) | CYP4F2CYP4A11RETGAA | |
| SCHEMBL26404733 | 0.79 | RET (0.35) | CYP4F2CYP4A11RETGAA | |
| SCHEMBL31393084 | 0.79 | CYP4F2 (0.32) | CYP4F2CYP4A11RET | |
| SCHEMBL20974775 | 0.79 | CYP4F2 (0.40) | CYP4F2CYP4A11RETATR | |
| SCHEMBL31393242 | 0.77 | RET (0.35) | CYP4F2CYP4A11RETATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713330-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235286-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |
| EP-4322954-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | Merck Sharp & Dohme LLC (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022221739-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-10-20 | — | — | WO | disclosed |