Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.40 |
| ▸ | GSK3A | P49840 | 8/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26131410 | 1.00 | GSK3B (0.40) | GSK3BGSK3AAAK1CDK2PIM1 | |
| SCHEMBL26396836 | 0.95 | GSK3B (0.41) | GSK3BGSK3AAAK1CDK2PIM1 | |
| SCHEMBL26129555 | 0.88 | GSK3B (0.42) | GSK3BGSK3AAAK1CDK2PIM1 | |
| Trifluoroacetic Acid SCHEMBL31243591 | 0.86 | GSK3B (0.45) | GSK3BGSK3AKDRDYRK1A | |
| Trifluoroacetic Acid SCHEMBL26128579 | 0.86 | GSK3B (0.45) | GSK3BGSK3AKDRDYRK1A | |
| Trifluoroacetic Acid SCHEMBL31243453 | 0.84 | GSK3A (0.46) | GSK3BGSK3AAAK1CDK2PIM1 | |
| Trifluoroacetic Acid SCHEMBL26130592 | 0.84 | GSK3A (0.46) | GSK3BGSK3AAAK1CDK2PIM1 | |
| Trifluoroacetic Acid SCHEMBL26130669 | 0.84 | GSK3A (0.46) | GSK3BGSK3AAAK1CDK2PIM1 | |
| Trifluoroacetic Acid SCHEMBL31243409 | 0.84 | GSK3A (0.46) | GSK3BGSK3AAAK1CDK2PIM1 | |
| Hydrochloric Acid SCHEMBL26132402 | 0.83 | ULK1 (0.43) | GSK3BGSK3AAAK1CDK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974020-A | Substituted 3-aminoindazole derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118974020-A | Substituted 3-aminoindazole derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2024-11-15 | — | — | CN | disclosed |