Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31243787 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL6461004 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7021740 | 0.87 | KDM4E (0.68) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL1421689 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL28383673 | 0.85 | KDM4E (0.66) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL27220349 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL13779328 | 0.83 | KDM4E (0.75) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL7018012 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| SCHEMBL6466480 | 0.82 | ADORA1 (0.63) | KDM4EALDH1A1RXFP1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7015693 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1RXFP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180162-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| US-12180161-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | claimed |
| US-12180162-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
| US-12180162-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
| US-12180161-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
| US-12180161-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
| US-12180161-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12180161-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | CASP4, DCUN1D4, DCUN1D5 | KDM4E 363/4885ALDH1A1 1862/4885RXFP1 4579/4885 |
| US-12180162-B1 | 2-amino-4-(4-bromophenyl)-6-methoxypyridine-3,5-dicarbonitrile as an antibacterial compound | CASP4, DCUN1D4, DCUN1D5 | KDM4E 355/4885ALDH1A1 1857/4885RXFP1 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.