Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244472 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL16505522 | 0.85 | L3MBTL1 (0.40) | KDM4EALDH1A1HPGDGAACYP1A2 | |
| SCHEMBL31285488 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL26092626 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL18189912 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL14507509 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL13764176 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL6934846 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL13764178 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL18189892 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695251-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024213656-A1 | IMIDAZO[1,2-A]PYRAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| CN-118684631-A | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) inhibitors, compositions and uses thereof | 中国科学院上海药物研究所 | 2024-09-24 | — | — | CN | disclosed |