Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303650 | 1.00 | KMO (0.46) | KMOACMSDDHODHHAO1TP53 | |
| SCHEMBL23294435 | 0.95 | KMO (0.47) | KMOACMSDDHODHHAO1TP53 | |
| SCHEMBL29851959 | 0.95 | KMO (0.47) | KMOACMSDDHODHHAO1TP53 | |
| SCHEMBL23294375 | 0.94 | MAP2K4 (0.45) | DHODHHAO1TP53MAP2K4MAPK1 | |
| SCHEMBL23294477 | 0.94 | MAP2K4 (0.45) | DHODHHAO1TP53MAP2K4MAPK1 | |
| SCHEMBL15946998 | 0.90 | KDM4E (0.46) | HAO1TP53MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL23294464 | 0.90 | KMO (0.54) | KMODHODHMAP2K4MAPK1MAPKAPK3 | |
| Hydrochloric Acid SCHEMBL3527570 | 0.89 | KDM4E (0.44) | HAO1TP53MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL23328966 | 0.88 | MAP2K4 (0.41) | HAO1MAP2K4MAPK1MAPKAPK3MAPK6 | |
| SCHEMBL23294377 | 0.88 | HAO1 (0.46) | KMOHAO1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051667-B1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | LILAC THERAPEUTICS INC (US) | 2026-01-28 | — | — | EP | disclosed |
| CN-114929676-B | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2025-04-29 | — | — | CN | disclosed |
| EP-4470538-A2 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | Lilac Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |