Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31246476 | 0.91 | PARP1 (0.47) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL25574315 | 0.91 | PARP1 (0.47) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL31016583 | 0.89 | MKNK1 (0.38) | ESR2MKNK1MTORC5AR1PARP1 | |
| SCHEMBL417213 | 0.85 | ESR2 (0.45) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL30887681 | 0.85 | ESR2 (0.45) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL31067085 | 0.84 | ESR2 (0.47) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL31246446 | 0.83 | MAPT (0.40) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL15440653 | 0.81 | ACHE (0.49) | MAPTESR2MTORC5AR1PDE10A | |
| SCHEMBL31623613 | 0.81 | MAPT (0.42) | MAPTESR2MKNK1MTORADORA1 | |
| SCHEMBL31014063 | 0.81 | MTOR (0.42) | MAPTESR2MTORADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024235876-A1 | PYRIDOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | FERNANDEZ CAPETILLO OSCAR (SE) | 2024-11-21 | — | — | WO | disclosed |