Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046825 | 0.91 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8735561 | 0.89 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8061917 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL312380 | 0.82 | KDM4E (0.84) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL312663 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10739914 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL11185030 | 0.82 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL8057309 | 0.82 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL10738181 | 0.81 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL7541073 | 0.81 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093381-B2 | Method of synthesis of fluoroquinolones | BIOCODEX (FR) | 2012-01-10 | — | — | US | disclosed |
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | BIOCODEX (FR) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | NQO2, Q6ZSR9, QARS1 | KDM4E 2435/4885HSD17B10 1768/4885ALDH1A1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.