Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964190 | 0.80 | KDM4E (0.55) | ACHEMAP2K1STSMAOBRAF1 | |
| SCHEMBL3124713 | 0.79 | ACHE (0.42) | ACHEMAP2K1STSMAOBRAF1 | |
| SCHEMBL961248 | 0.77 | HSD17B3 (0.55) | ACHEHPGD | |
| SCHEMBL12521082 | 0.70 | HSD17B3 (0.53) | ACHEHPGD | |
| SCHEMBL960510 | 0.67 | KDM4E (0.49) | ACHEMAP2K1STSMAOBRAF1 | |
| SCHEMBL959803 | 0.64 | HSD17B3 (0.51) | ACHEHPGD | |
| SCHEMBL960703 | 0.63 | MAP2K1 (0.70) | ACHEMAP2K1STSRAF1HPGD | |
| SCHEMBL12702266 | 0.63 | KDM4E (0.51) | ACHEMAP2K1STSMAOBRAF1 | |
| SCHEMBL959085 | 0.63 | MAP2K1 (0.53) | ACHEMAP2K1MAOBRAF1HPGD | |
| SCHEMBL31980592 | 0.63 | MAP2K1 (0.70) | ACHEMAP2K1STSRAF1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172198-A1 | p27 PROTEIN INDUCER | Chugai Seiyaku Kabushiki Kaisha (JP) | 2010-04-07 | — | — | EP | disclosed |