Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | PTPRG | P23470 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396500 | 0.76 | ADRA2A (0.41) | MAPTALDH1A1TDP1KMT2AADRA2A | |
| SCHEMBL2441511 | 0.74 | ADRA2A (0.40) | MAPTALDH1A1PKMTDP1SMN1; SMN2 | |
| SCHEMBL6057233 | 0.73 | POLB (0.57) | POLBMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL3623024 | 0.72 | CYP19A1 (0.49) | ADRA2AADRA2B | |
| SCHEMBL31726141 | 0.72 | POLB (0.47) | PTPRCPOLBMAPTALDH1A1PKM | |
| SCHEMBL31449914 | 0.72 | POLB (0.44) | PTPRCPOLBMAPTALDH1A1PKM | |
| SCHEMBL24904974 | 0.71 | ADRA2A (0.38) | MAPTALDH1A1PKMKMT2AADRA2A | |
| SCHEMBL28396501 | 0.71 | ADRA2A (0.38) | MAPTALDH1A1ADRA2AADRA2BHTT | |
| SCHEMBL19114848 | 0.70 | PTPRC (0.58) | PTPRCPOLBMAPTALDH1A1PKM | |
| SCHEMBL23531772 | 0.70 | PTPRC (0.50) | PTPRCPOLBMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217519-A1 | PYRROLE SULFONYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天地恒一制药股份有限公司 | 2024-10-24 | — | — | WO | disclosed |