Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 7/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426049 | 0.83 | LMNA (0.40) | MAPTSMN1; SMN2LMNAPRKDCHTR1A | |
| SCHEMBL31425997 | 0.81 | PRKDC (0.46) | MAPTLMNAPRKDCPIK3CDPIK3CA | |
| SCHEMBL30993545 | 0.76 | MAPT (0.51) | MAPTSMN1; SMN2HSD17B10POLBTP53 | |
| SCHEMBL31426020 | 0.74 | LMNA (0.38) | MAPTSMN1; SMN2LMNAPRKDCHTR1A | |
| SCHEMBL30993100 | 0.74 | MAPT (0.41) | MAPTSMN1; SMN2ALOX15HSD17B10CCR5 | |
| SCHEMBL31248706 | 0.74 | MAOB (0.38) | MAPTLMNAHTR1ADRD2HSD17B10 | |
| SCHEMBL30445159 | 0.72 | HSD17B10 (0.35) | HSD17B10POLB | |
| SCHEMBL16362080 | 0.72 | HSD17B10 (0.35) | HSD17B10POLB | |
| SCHEMBL16932363 | 0.71 | HSD17B10 (0.34) | LMNAHTR1ADRD2ALOX15HSD17B10 | |
| SCHEMBL30538016 | 0.71 | JAK2 (0.35) | LMNAHSD17B10POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720057-A2 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249888-A2 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2024-12-05 | — | — | WO | disclosed |