SCHEMBL31248619

SCHEMBL31248619

O=C1CCC(Nc2cncc(Br)c2)C(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.61
CRBN Q96SW2 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25810617 0.83 DDB1 (0.61) DDB1CRBN
SCHEMBL31103036 0.83 DDB1 (0.57) DDB1CRBN
SCHEMBL31099830 0.81 DDB1 (0.59) DDB1CRBN
SCHEMBL31103279 0.80 DDB1 (0.67) DDB1CRBN
SCHEMBL31099825 0.80 DDB1 (0.57) DDB1CRBN
SCHEMBL31100418 0.80 DDB1 (0.57) DDB1CRBN
SCHEMBL27241641 0.78 CRBN (0.72) DDB1CRBN
SCHEMBL31248969 0.76 DDB1 (0.53) DDB1CRBN
SCHEMBL21965398 0.76 DDB1 (1.00) DDB1CRBN
SCHEMBL31102263 0.74 DDB1 (0.50) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed