SCHEMBL25810617

SCHEMBL25810617

Cc1cncc(NC2CCC(=O)NC2=O)c1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.61
CRBN Q96SW2 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31248619 0.83 DDB1 (0.61) DDB1CRBN
SCHEMBL31099830 0.81 DDB1 (0.59) DDB1CRBN
SCHEMBL31103036 0.80 DDB1 (0.57) DDB1CRBN
SCHEMBL31099825 0.80 DDB1 (0.57) DDB1CRBN
SCHEMBL31103279 0.80 DDB1 (0.67) DDB1CRBN
SCHEMBL31100418 0.80 DDB1 (0.57) DDB1CRBN
SCHEMBL21965746 0.79 DDB1 (0.72) DDB1CRBN
SCHEMBL21965448 0.78 DDB1 (0.72) DDB1CRBN
SCHEMBL25833426 0.78 DDB1 (0.72) DDB1CRBN
SCHEMBL25810615 0.78 DDB1 (0.63) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116934-A1 KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州泽璟生物制药股份有限公司 2023-06-29 WO disclosed