SCHEMBL31248890

SCHEMBL31248890

Cc1cc2ccc(C3CCOCC3)cc2n(C)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 1/20 0.48
BRD4 O60885 11/20 0.46
BRPF1 P55201 3/20 0.41
LRRK2 Q5S007 1/20 0.40
PDE1B Q01064 2/20 0.39
TDP2 O95551 1/20 0.37
BAZ2A Q9UIF9 4/20 0.36
PDE1A P54750 1/20 0.36
PDE1C Q14123 1/20 0.36
PTPN11 Q06124 1/20 0.36
TAF1 P21675 1/20 0.36
BRD2 P25440 1/20 0.36
EP300 Q09472 1/20 0.36
BRD3 Q15059 1/20 0.36
BRDT Q58F21 1/20 0.36
CREBBP Q92793 1/20 0.36
CECR2 Q9BXF3 1/20 0.36
BRD9 Q9H8M2 1/20 0.36
BAZ2B Q9UIF8 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31248760 0.76 PDE1B (0.38) HTR1DBRD4BRPF1PDE1BTDP2
SCHEMBL29471257 0.76 PDE1B (0.38) HTR1DBRD4BRPF1PDE1BTDP2
SCHEMBL26112688 0.76 PDE1B (0.38) HTR1DBRD4BRPF1PDE1BTDP2
SCHEMBL26111817 0.74 BRD4 (0.41) BRD4BRPF1PDE1BPDE1APDE1C
SCHEMBL29471279 0.74 BRD4 (0.41) BRD4BRPF1PDE1BPDE1APDE1C
SCHEMBL18000278 0.71 HTR1D (0.39) HTR1DLRRK2KDM4EALDH1A1HPGD
SCHEMBL19448891 0.71 BRPF1 (0.54) BRD4BRPF1BRD9KDM4EALDH1A1
SCHEMBL31425963 0.69 PDE1B (0.39) HTR1DBRD4BRPF1PDE1BTDP2
SCHEMBL14183099 0.69 HTR1D (0.41) HTR1DBRD4GAA
SCHEMBL12992386 0.68 BRPF1 (0.75) BRD4BRPF1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed