SCHEMBL31248977

SCHEMBL31248977

NCC#Cc1cccc(NC2CCC(=O)NC2=O)c1F

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.51
DDB1 Q16531 18/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31248691 0.82 CRBN (0.48) CRBNDDB1
SCHEMBL30993448 0.81 CRBN (0.67) CRBNDDB1
SCHEMBL31248694 0.79 CRBN (0.49) CRBNDDB1
SCHEMBL25810612 0.76 CRBN (0.60) CRBNDDB1
SCHEMBL31248852 0.76 DDB1 (0.67) CRBNDDB1
SCHEMBL31248965 0.76 DDB1 (0.67) CRBNDDB1
SCHEMBL31248847 0.76 DDB1 (0.67) CRBNDDB1
Hydrochloric Acid SCHEMBL31248612 0.75 DDB1 (0.65) CRBNDDB1
SCHEMBL30797165 0.73 CRBN (0.56) CRBNDDB1
SCHEMBL27274936 0.73 CRBN (0.56) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed